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Week 16 Fantasy Football Guide

Updated: 9 hours ago

By: Jake Weiner

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The Fantasy Football Semi-Finals are here! Week 16 of the NFL season brings plenty of high-stakes matchups as teams fight for playoff positioning and fantasy managers scramble to set their final lineups. From the Eagles looking to cement their NFC dominance to the Jags aiming to keep their postseason hopes alive, this week features a mix of high-powered offenses and defensive battles. Injuries, matchups, and game scripts will play a major role in fantasy outcomes, making strategic starts, sits, and streamer plays crucial. Let’s break down the key players you need to know for Week 16, along with the spreads and top fantasy plays.

Seattle Seahawks @ Los Angeles Rams — Thursday, Week 16, 8:15 PM ET


Quick Take:


The Seahawks travel to LA for a Thursday night showdown with the Rams. Seattle enters as a slight underdog but carries momentum behind QB Sam Darnold and emerging WR Rashid Shaheed. The Rams are facing questions at WR, with Davante Adams coming down with a hamstring injury. This game is expected to be close, with both offenses leaning on their passing attacks. Seattle’s upside in fantasy could come from Darnold connecting with JSN and Shaheed at WR in a potentially shootout-like scenario.


Pick: Seahawks pull the upset — SEA cover (SEA +1.5).



Injury Report:


Seahawks:

  • RB Kenneth Walker III — status TBD, limited participation


Rams:

  • WR Davante Adams — status OUT, no participation



Fantasy Start & Forget It:


Seahawks:

  • WR Jaxson Smith-Njigba — Top 4 WR


Rams:

  • WR Puka Nacua — Top 4 WR



Fantasy Starts:


Seahawks:

  • K Jason Myers — Top 8 K


Rams:

  • RB Kyren Williams — Top 18 RB

  • TE Colby Parkinson — Top 10 TE



Fantasy Flex / Risky Starts / Flex Appeal:


Seahawks:

  • QB Sam Darnold — Top 12 QB

  • WR Rashid Shaheed — Top 30 WR


Rams:

  • None



Fantasy Sits / Fades:


Seahawks:

  • RB Kenneth Walker III — 68% started

  • WR Cooper Kupp — 24% started

  • TE AJ Barner — 33% started


Rams:

  • QB Matthew Stafford — 83% started

  • RB Blake Corum — 43% started

  • WR Tutu Atwell — 31% started

  • Rams Defense — 55% started



Sneaky / Streamer Plays:


Seahawks:

  • QB Sam Darnold — 21% Rostered

  • WR Rashid Shaheed — 19% Rostered


Rams:

  • TE Colby Parkinson — 19% Rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Seahawks 33 - Rams 27


Seahawks:

QB Sam Darnold - 256 pass yards, 2 pass TDs, 1 INT

RB Kenneth Walker III - 10 carries, 31 rush yards, 3 catches, 18 rec yards

RB Zach Charbonnet - 8 carries, 35 rush yards, 1 rush TD

WR JSN - 8/109/1

WR Rashid Shaheed - 4/63/1

WR Cooper Kupp - 4/41

TE AJ Barner - 3/27

K Jason Myers - 4/4 FG, 3/3 PAT


Rams:

QB Matthew Stafford - 247 pass yards, 2 pass TDs, 2 INT

RB Blake Corum - 10 carries, 66 rush yards, 1 rush TD, 1 catch, 9 rec yards

RB Kyren Williams - 14 carries, 71 rush yards, 1 rush TD, 1 catch, 10 rec yards

WR Tutu Atwell - 2/34

WR Puka Nacua - 7/168

TE Colby Parkinson - 4/68/1

K Harrison Mervis - 2/3 FG, 3/3 PAT



Betting Plays:

  • Sam Darnold OVER 223.5 pass yards

  • Matthew Stafford OVER 1.5 pass TDs

  • Kyren Williams UNDER 13.5 rush attempts

  • Kenneth Walker III UNDER 12.5 rush attempts

  • Zach Charbonnet OVER 33.5 rush yards

  • Kyren Williams OVER 53.5 rush yards

  • Puka Nacua 80+ yards

  • JSN OVER 6.5 receptions

  • Longshot TD: Rashid Shaheed

  • Longshot TD: Colby Parkinson


Washington Commanders @ Philadelphia Eagles — Saturday, Week 16, 5:00 PM ET


Quick Take:


The Eagles host Washington in a divisional matchup with major playoff implications for the Eagles. Philadelphia holds clear advantages on both sides of the ball and enters as a touchdown favorite behind an elite fantasy core led by Jalen Hurts and Saquon Barkley. Washington’s offense is more limited, relying heavily on Terry McLaurin and Deebo Samuel and hoping to stay competitive through game script. Unless turnovers swing this early, the Eagles should control possession and scoring throughout.


Pick: Eagles win — likely cover (PHI -6).



Injury Report:


Commanders

  • RB Chris Rodriguez — limited, not expected to have a major role

  • WR Noah Brown — OUT



Eagles

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Commanders

  • None


Eagles

  • QB Jalen Hurts — Elite QB1

  • RB Saquon Barkley — Elite RB1

  • WR AJ Brown — Locked-in WR1

  • Eagles Defense — Top-tier D/ST



Fantasy Starts:


Commanders

  • K Jake Moody — Top streaming kicker


Eagles

  • WR Devonta Smith — Mid-end WR2

  • TE Dallas Goedert — Strong TE1



Fantasy Flex / Risky Starts / Flex Appeal:


Commanders

  • WR Terry McLaurin — Low-End WR2 / High-End WR3

  • RB JCM — Volume-based low-end Flex


Eagles

  • K Jake Elliott — Mid-End streaming kicker



Fantasy Sits / Fades:


Commanders

  • RB Chris Rodriguez — 23% started

  • WR Deebo Samuel — 48% started


Eagles

  • None



Sneaky / Streamer Plays:


Commanders

  • RB JCM — 19% rostered

  • K Jake Moody — 5% rostered


Eagles

  • Eagles Defense — 29% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Eagles 34 - Commanders 13


Commanders

  • QB Marcus Mariota - 209 pass yards, 1 INT, 5 carries, 41 rush yards

  • RB Jacory Croskey-Merritt - 7 carries, 29 rush yards, 1 rush TD

  • RB Chris Rodriguez - 11 carries, 34 rush yards, 1 catch, 9 rec yards

  • WR Terry McLaurin - 3/41

  • WR Deebo Samuel - 4/27

  • TE Ben Sinnott - 2/33

  • K Jake Moody - 2/3 FG, 1/1 PAT



Eagles

  • QB Jalen Hurts - 218 pass yards, 3 pass TD, 5 carries, 31 rush yards

  • RB Saquon Barkley - 20 carries, 83 rush yards, 1 rush TD, 2 catches, 16 rec yards

  • RB Tank Bigsby - 14 carries, 61 rush yards

  • WR AJ Brown - 7/106/1

  • WR Devonta Smith - 5/61/1

  • TE Dallas Goedert - 4/51/1

  • K Jake Elliott - 2/2 FG, 3/3 PAT




Betting Plays:

  • Eagles -10

  • Marcus Mariota OVER 204.5 pass yards

  • Jalen Hurts OVER 1.5 pass TDs

  • Marcus Mariota OVER 0.5 INTs

  • Jalen Hurts UNDER 7.5 carries

  • Jalen Hurts OVER 25.5 rush yards

  • JCM OVER 27.5 rush yards

  • Longshot TD: JCM


Chicago Bears @ Green Bay Packers — Saturday, Week 16, 8:20 PM ET


Quick Take:


This NFC North clash sets up as one of the tighter games of the weekend. Chicago comes in as a slight underdog but has clear fantasy paths through the run game and younger skill players, while Green Bay leans on Jordan Love and his wide receiver trio to generate offense. With both defenses inconsistent, this game projects as competitive throughout, giving Chicago a real chance to steal one late.


Pick: Bears win — CHI cover (CHI +2).



Injury Report:


Bears

  • WR Rome Odunze — OUT, Chest


Packers

  • WR Christian Watson — ACTIVE, Chest

  • LB Micah Parsons — OUT, ACL Tear



Fantasy Start & Forget It:


Bears

  • RB D’Andre Swift — Mid-end RB1


Packers

  • QB Jordan Love — Strong QB1



Fantasy Starts:


Bears

  • K Cairo Santos— Strong Kicker


Packers

  • WR Jayden Reed — WR2 WITH BOOM POTENTIAL IF NO WATSON



Fantasy Flex / Risky Starts / Flex Appeal:


Bears

  • RB Kyle Monangai — RB3 with upside

  • TE Colston Loveland — Streaming TE


Packers

  • WR Romeo Doubs — Boom/bust flex (NO WATSON --> FRINGE START)

  • Packers Defense — Low-End Defense 1



Fantasy Sits / Fades:


Bears

  • QB Caleb Williams — 44% started


Packers

  • WR Christian Watson — 66% started (IF ACTIVE)

  • K Brandon McManus — 55% started



Sneaky / Streamer Plays:


Bears

  • K Cairo Santos — 29% rostered


Packers

  • WR Romeo Doubs — 18% rostered

  • WR Jayden Reed — 27% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Bears 27 - Packers 23


Bears

  • QB Caleb Williams - 211 pass yards, 1 pass TD, 1 INT, 3 carries, 11 rush yards

  • RB D’Andre Swift - 17 carries, 94 rush yards, 1 rush TD, 1 catch, 17 rec yards

  • RB Kyle Monangai - 12 carries, 55 rush yards, 1 rush TD

  • WR DJ Moore - 6/71/1

  • TE Colston Loveland - 4/52

  • K Cairo Santos - 2/2 FG, 3/3 PAT


Packers

  • QB Jordan Love - 239 pass yards, 2 pass TDs, 1 INT, 3 carries, 22 rush yards

  • RB Emmanuel Wilson - 19 carries, 82 rush yards, 1 rush TD, 2 catches, 16 rec yards

  • WR Jayden Reed - 5/62

  • WR Romeo Doubs - 3/32/1

  • WR Christian Watson - 4/41/1

  • TE Luke Musgrave - 3/28

  • K Brandon McManus - 1/2 FG, 3/3 PAT



Betting Plays:

  • Jordan Love OVER 231.5 pass yards

  • Jordan Love OVER 1.5 pass TDs

  • Caleb Williams UNDER 1.5 pass TDs

  • Caleb Williams OVER 3.5 carries

  • Kyle Monangai OVER 10.5 carries

  • D'Andre Swift OVER 51.5 rush yards

  • D'Andre Swift OVER 12.5 carries

  • Josh Jacobs OVER 65.5 rush yards

  • Jayden Reed OVER 40.5 rec yards

  • Josh Jacobs anytime TD

  • Longshot TD: Kyle Monangai

  • Longshot TD: Josh Jacobs 2+


Minnesota Vikings @ New York Giants — Sunday, Week 16, 1:00 PM ET


Quick Take:


This matchup projects as a tight, low-margin game with both teams leaning on young quarterbacks and aggresive game plans. Minnesota holds the slight edge thanks to better defensive structure and a steadier kicking game, while New York’s fantasy value is concentrated in Jaxson Dart’s passing volume and rushes. Expect a close contest where turnovers and field position matter more than explosive plays.


Pick: Vikings win — likely cover (MIN -1.5).



Injury Report:


Vikings

  • No listed injuries impacting fantasy this week


Giants

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Vikings

  • None


Giants

  • None



Fantasy Starts:


Vikings

  • RB Aaron Jones Sr — RB2

  • K Will Reichard — Strong kicking play

  • Vikings Defense — Top streaming D/ST


Giants

  • WR Wan’Dale Robinson — Mid-End PPR WR2

  • QB Jaxson Dart — Volume-based QB1/2



Fantasy Flex / Risky Starts / Flex Appeal:


Vikings

  • QB JJ McCarthy — Safe QB2 with High upside

  • RB Jordan Mason — Flex RB


Giants

  • TE Theo Johnson — Red-zone upside / High-End TE2

  • Giants Defense — Mid streaming D/ST



Fantasy Sits / Fades:


Vikings

  • WR Justin Jefferson — 95% started

  • WR Jordan Addison — 48% started

  • TE TJ Hockenson — 48% started


Giants

  • RB Tyrone Tracy — 41% started

  • WR Darius Slayton — 39% started



Sneaky / Streamer Plays:


Vikings

  • Vikings Defense — 12% rostered


Giants

  • TE Theo Johnson — 30% rostered

  • Giants Defense — 2% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Vikings 24 - Giants 20


Vikings

  • QB JJ McCarthy - 219 pass yards, 2 pass TD, 1 INT, 6 carries, 54 rush yards

  • RB Aaron Jones Sr - 14 carries, 66 rush yards, 1 rush TD, 3 catches, 29 rec yards

  • RB Jordan Mason - 10 carries, 51 rush yards

  • WR Justin Jefferson - 4/42

  • WR Jordan Addison - 4/51

  • WR Jalen Nailor - 3/31

  • TE TJ Hockenson - 3/39/1

  • TE Josh Oliver - 2/18/1

  • K Will Reichard - 1/1 FG, 3/3 PAT


Giants

  • QB Jaxson Dart - 187 pass yards, 2 pass TD, 1 INT, 4 carries, 41 rush yards

  • RB Tyrone Tracy - 13 carries, 44 rush yards, 4 catches, 44 rec yards

  • RB Devin Singletary - 9 carries, 32 rush yards, 1 catch, 7 rec yards

  • WR Wan’Dale Robinson - 6/56/1

  • WR Darius Slayton - 3/43

  • TE Theo Johnson - 3/49/1

  • K Ben Sauls - 2/3 FG, 2/2 PAT



Betting Plays:

  • Tyrone Tracy OVER 12.5 carries

  • JJ McCarthy OVER 3.5 carries

  • Theo Johnson OVER 31.5 yards

  • MIN NYG OVER 44.5 points

  • TJ Hockenson OVER 2.5 receptions

  • Longshot TD: Jordan Mason


Tampa Bay Buccaneers @ Carolina Panthers — Sunday, Week 16, 1:00 PM ET


Quick Take:


Tampa Bay heads to Carolina in a matchup that sets up well for the Buccaneers to control tempo. Baker Mayfield has been steady, and Tampa’s offense should be able to take advantage of a Panthers team that struggles to sustain drives. Carolina’s fantasy value is concentrated almost entirely in the backfield, while Tampa offers a safer QB start and a clearer offensive structure with so many WRs to look at. This game profiles as competitive with Tampa taking it home in the end.


Pick: Buccaneers win — likely cover (TB -1.5).



Injury Report:


Buccaneers

  • No listed injuries impacting fantasy this week


Panthers

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Panthers

  • None


Buccaneers

  • RB Bucky Irving — Mid-End RB1



Fantasy Starts:


Panthers

  • RB Rico Dowdle — Volume-based RB2


Buccaneers

  • WR Mike Evans — High-End Reliable WR2

  • K Chase McLaughlin — Mid-End Reliable Kicker



Fantasy Flex / Risky Starts / Flex Appeal:


Panthers

  • WR Tetairoa McMillan — Touchdown-dependent/Volume-Based flex

  • WR Jalen Coker — Touchdown-dependent/Volume-Based flex


Buccaneers

  • QB Baker Mayfield — Low-End Reliable QB1

  • WR Emeka Egbuka — High-End Reliable WR3

  • RB Sean Tucker — High-End Reliable RB3 WITH TD UPSIDE



Fantasy Sits / Fades:


Panthers

  • RB Chubba Hubbard — 41% started


Buccaneers

  • WR Chris Godwin — 52% started

  • Buccaneers Defense — 39% started



Sneaky / Streamer Plays:


Panthers

  • WR Jalen Coker — 18% rostered


Buccaneers

  • RB Sean Tucker — 7% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Buccaneers 20 - Panthers 17


Buccaneers

  • QB Baker Mayfield - 251 pass yards, 1 pass TD, 1 INT, 4 carries, 23 rush yards

  • RB Bucky Irving - 16 carries, 66 rush yards, 2 catches, 28 rec yards, 1 rec TD

  • RB Sean Tucker - 4 carries, 13 rush yards, 1 rush TD

  • RB Rachaad White - 4 carries, 18 rush yards, 2 catches, 16 rec yards

  • WR Mike Evans - 5/78

  • WR Chris Godwin - 3/32

  • WR Emeka Egbuka - 5/71

  • WR Jalen McMillan - 3/39

  • K Chase McLaughlin - 2/2 FG, 2/2 PAT


Panthers

  • QB Bryce Young - 168 pass yards, 1 pass TD, 1 INT, 5 carries, 24 rush yards

  • RB Rico Dowdle - 15 carries, 51 rush yards, 1 rush TD, 1 catch, 4 rec yards

  • RB Chubba Hubbard - 11 carries, 32 rush yards, 3 catches, 29 rec yards

  • WR Tetairoa McMillan - 3/41

  • WR Jalen Coker - 4/52/1

  • WR Xavier Leggette - 2/37

  • K Ryan Fitzgerald - 1/1 FG, 2/2 PAT



Betting Plays:

  • Bucky Irving OVER 18.5 rec yards

  • Alec Pierce OVER 24.5 rec yards

  • Longshot TD: Jalen Coker

  • Longshot TD: Sean Tucker


Buffalo Bills @ Cleveland Browns — Sunday, Week 16, 1:00 PM ET


Quick Take:


Buffalo enters this matchup as heavy favorites and should be able to dictate game script from the opening drive. The Bills’ defense sets up as a strong fantasy play against a Browns offense dealing with inefficiency and limited upside outside the tight end position. Cleveland may struggle to keep pace if Buffalo jumps out early, making this a spot where defensive pressure and field position swing the game quickly.


Pick: Bills win — likely cover (BUF -8.5).



Injury Report:


Bills

  • No listed injuries impacting fantasy this week


Browns

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Browns

  • None


Bills

  • QB Josh Allen — Elite QB1

  • RB James Cook — Elite RB1

  • Bills Defense — Elite D/ST play



Fantasy Starts:


Browns

  • RB Quinshon Judkins — High-End RB2

  • TE Harold Fannin Jr — High-End TE1


Bills

  • None



Fantasy Flex / Risky Starts / Flex Appeal:


Browns

  • None


Bills

  • WR Khalil Shakir — High-End WR3

  • TE Dalton Kincaid — Low-End TE1

  • TE Dawson Knox — Red-zone dependent TE2



Fantasy Sits / Fades:


Bills

  • None


Browns

  • WR Jerry Jeudy — 39% started

  • Browns Defense — 46% started



Sneaky / Streamer Plays:


Bills

  • Bills Defense — 31% rostered


Browns

  • TE Harold Fannin Jr — 53% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Bills 38 - Browns 10


Bills

  • QB Josh Allen - 237 pass yards, 3 pass TDs, 1 INT, 8 carries, 63 rush yards, 1 rush TD

  • RB James Cook - 21 carries, 103 rush yards, 1 rush TD, 2 catches, 18 rec yards

  • RB Ty Johnson - 3 carries, 7 rush yards, 3 catches, 17 rec yards

  • WR Khalil Shakir - 6/52

  • WR Keon Coleman - 2/26/1

  • TE Dalton Kincaid - 4/39/1

  • TE Dawson Knox - 2/28/1

  • K Michael Badgley - 1/1 FG, 5/5 PAT


Browns

  • QB Shedeur Sanders - 184 pass yards, 1 INT, 2 carries, 24 rush yards

  • RB Quinshon Judkins - 16 carries, 94 rush yards, 1 rush TD, 2 catches, 24 rec yards

  • WR Jerry Jeudy - 3/26

  • WR Isaiah Bond - 2/45

  • TE Harold Fannin Jr - 7/68

  • K Andrey Szmyt - 1/1 FG, 1/1 PAT



Betting Plays:

  • Bills -6

  • Josh Allen OVER 215.5 pass yards

  • Shedeur Sanders UNDER 177.5 pass yards

  • Shedeur Sanders OVER 0.5 INTs

  • Josh Allen OVER 7.5 carries

  • Josh Allen OVER 34.5 rush yards

  • Quinshon Judkins OVER 61.5 rush yards

  • Dalton Kincaid OVER 2.5 receptions

  • Dawson Knox OVER 2.5 receptions

  • Ty Johnson OVER 2.5 receptions

  • Longshot TD: Bills D/ST



Los Angeles Chargers @ Dallas Cowboys — Sunday, Week 16, 1:00 PM ET


Quick Take:


This matchup is expected to be one of the more competitive games on the early slate. Dallas comes in as a slight underdog but has clear paths to fantasy production through Javonte Williams, Ceedee Lamb, and defensive pressure. The Chargers will lean on Justin Herbert and a concentrated receiving group, though inconsistency in the run game keeps this one closer than expected. Expect a back-and-forth contest that stays within one score for most of the afternoon.


Pick: Chargers win — LAC cover (LAC -2.5).



Injury Report:


Cowboys

  • No listed injuries impacting fantasy this week


Chargers

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Cowboys

  • WR Ceedee Lamb — Locked-in WR1

  • K Brandon Aubrey — Elite Kicker


Chargers

  • K Cam Dicker — Elite Kicker



Fantasy Starts:


Cowboys

  • RB Javonte Williams — High-End RB2

  • WR George Pickens — Low-End WR2


Chargers

  • WR Justin Herbert — Matchup-Based Low-End QB1

  • WR Ladd McConkey — WR2



Fantasy Flex / Risky Starts / Flex Appeal:


Cowboys

  • Cowboys Defense — Streamable D/ST


Chargers

  • RB Omarion Hampton — Low-End RB2 RISKY

  • WR Keenan Allen — PPR High-End WR3

  • TE Oronde Gadsden — Low-End TE1

  • Chargers Defense — Streamable D/ST



Fantasy Sits / Fades:


Cowboys

  • QB Dak Prescott — 82% started


Chargers

  • RB Kimani Vidal — 55% started



Sneaky / Streamer Plays:


Cowboys

  • Cowboys Defense — 7% rostered


Chargers

  • WR Keenan Allen — 42% rostered

  • Chargers Defense — 19% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Chargers 27 - Cowboys 23


Cowboys

  • QB Dak Prescott - 284 pass yards, 1 pass TD, 1 INT

  • RB Javonte Williams - 15 carries, 84 rush yards, 1 rush TD, 2 catches, 17 rec yards

  • WR George Pickens - 5/71/1

  • WR Ceedee Lamb - 6/114

  • TE Jake Ferguson - 4/39

  • K Brandon Aubrey - 3/3 FG, 3/3 PAT


Chargers

  • QB Justin Herbert - 255 pass yards, 2 pass TDs, 3 carries, 18 rush yards

  • RB Omarion Hampton - 14 carries, 56 rush yards, 2 catches, 16 rec yards

  • RB Kimani Vidal - 10 carries, 33 rush yards, 1 catch, 9 rec yards

  • WR Keenan Allen - 4/51/1

  • WR Ladd McConkey - 5/87/1

  • TE Oronde Gadsden - 4/58

  • K Cam Dicker - 2/2 FG, 3/3 PAT



Betting Plays:

  • LAC DAL 45+ points

  • Kimani Vidal longest reception OVER 9.5 yards

  • Justin Herbert longest rush OVER 8.5 yards

  • Javonte Williams anytime TD

  • George Pickens OVER 4.5 receptions

  • Omarion Hampton OVER 11.5 carries

  • Longshot TD: Keenan Allen


New York Jets @ New Orleans Saints — Sunday, Week 16, 1:00 PM ET


Quick Take:


The Saints host the Jets in a matchup that favors New Orleans due to offensive stability and defensive consistency. The Jets continue to struggle to generate reliable production outside of sporadic big plays, while the Saints lean on Tyler Shough managing the offense and Chris Olave serving as the clear focal point. With New York prone to mistakes and New Orleans able to control tempo, this sets up as a solid home win for the Saints.


Pick: Saints win — likely cover (NO -3.5).



Injury Report:


Jets

  • QB Justin Fields — QUESTIONABLE

  • QB Tyrod Taylor — QUESTIONABLE

  • WR Garrett Wilson — DOUBTFUL


Saints

  • RB Devin Neal — OUT

  • RB Alvin Kamara — DOUBTFUL

  • WR Devaughn Vele — OUT



Fantasy Start & Forget It:


Saints

  • WR Chris Olave — Locked-in WR1/2

  • Saints Defense — Strong D/ST play


Jets

  • None



Fantasy Starts:


Saints

  • QB Tyler Shough — Streaming QB

  • RB Audric Estime — 1% started

  • TE Juwan Johnson — Low-End TE1 with upside


Jets

  • None



Fantasy Flex / Risky Starts / Flex Appeal:


Saints

  • None


Jets

  • None



Fantasy Sits / Fades:


Jets

  • RB Breece Hall — 64% started

  • WR AD Mitchell — 31% started


Saints

  • None



Sneaky / Streamer Plays:


Saints

  • QB Tyler Shough — 11% rostered

  • TE Juwan Johnson — 23% rostered


Jets

  • None



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Saints 24 - Jets 13


Jets

  • QB Brady Cook - 161 pass yards, 1 pass TD, 2 INTs

  • RB Breece Hall - 12 carries, 43 rush yards, 2 catches, 11 rec yards

  • WR AD Mitchell - 2/29/1

  • WR John Metchie - 4/21

  • K Nick Folk - 2/2 FG, 1/1 PAT


Saints

  • QB Tyler Shough - 189 pass yards, 1 pass TD, 8 carries, 44 rush yards, 1 rush TD

  • RB Audric Estime - 14 carries, 46 rush yards, 1 rush TD, 3 catches, 31 rec yards

  • WR Chris Olave - 6/81/1

  • TE Juwan Johnson - 5/58

  • K Charlie Smyth - 1/2 FG, 3/3 PAT



Betting Plays:

  • Saints -6

  • AD Mitchell longest reception OVER 20.5 yards

  • Tyler Shough longest rush OVER 10.5 yards

  • Jeremy Ruckert OVER 1.5 receptions

  • Breece Hall OVER 1.5 receptions

  • John Metchie 3+ catches

  • Longshot TD: Audric Estime


Kansas City Chiefs @ Tennessee Titans — Sunday, Week 16, 1:00 PM ET


Quick Take:


This matchup sets up as a grind-it-out game where Tennessee keeps things closer on the scoreboard than expected, but Kansas City still controls the outcome. The Chiefs’ offensive stars remain fantasy-relevant even in a tougher matchup, while the Titans’ value comes almost entirely from defensive pressure and limiting mistakes. Kansas City’s experience and efficiency should prevail late.


Pick: Chiefs win — Titans likely cover (TEN +11.5).



Injury Report:


Chiefs

  • No listed injuries impacting fantasy this week


Titans

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Chiefs

  • WR Rashee Rice — High-end WR2

  • Chiefs Defense — High-floor start


Titans

  • None



Fantasy Starts:


Chiefs

  • TE Travis Kelce — Low-End TE1


Titans

  • None



Fantasy Flex / Risky Starts / Flex Appeal:


Chiefs

  • TD Kareem Hunt — TD-based upside


Titans

  • Titans Defense — Streaming D/ST



Fantasy Sits / Fades:


Chiefs

  • K Harrison Butker — 71% started


Titans

  • RB Tony Pollard — 67% started



Sneaky / Streamer Plays:


Chiefs

  • Chiefs Defense — 33% rostered


Titans

  • Titans Defense — 1% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Chiefs 27 - Titans 13


Chiefs

  • QB Gardner Minshew - 219 pass yards, 2 pass TDs, 1 INT

  • RB Kareem Hunt - 9 carries, 23 rush yards, 1 rush TD, 1 catch, 4 rec yards

  • RB Isaiah Pacheco - 11 carries, 21 rush yards

  • WR Rashee Rice - 7/89/1

  • WR Xavier Worthy - 3/49

  • TE Travis Kelce - 6/52/1

  • K Harrison Butker - 2/2 FG, 3/3 PAT


Titans

  • QB Cam Ward - 156 pass yards, 0 pass TDs, 2 INTs

  • RB Tony Pollard - 14 carries, 89 rush yards, 1 rush TD, 1 catch, 12 rec yards

  • RB Tyjae Spears - 6 carries, 23 rush yards, 2 catches, 14 rec yards

  • WR Chimere Dike - 3/21

  • WR Elic Ayomanor - 1/19

  • TE Gunnar Helm - 4/41

  • K Joey Slye - 2/2 FG, 1/1 PAT



Betting Plays:

  • Travis Kelce longest reception OVER 16.5 yards

  • Xavier Worthy longest reception OVER 16.5 yards

  • Travis Kelce OVER 31.5 yards

  • Longshot TD: Kareem Hunt


Miami Dolphins @ Cincinnati Bengals — Sunday, Week 16, 1:00 PM ET


Quick Take:


This matchup has sneaky shootout potential with both teams leaning on their passing games. Cincinnati gets Joe Burrow back in a favorable spot, but Miami’s offensive flexibility and efficiency give them the edge as slight underdogs. The Dolphins’ fantasy production is concentrated through Jaylen Waddle, Devon Achane and Darren Waller, while Cincinnati’s scoring hinges on Burrow keeping pace. Expect a competitive game that comes down to late drives.


Pick: Bengals win — likely cover (CIN -1.5).



Injury Report:


Dolphins

  • QB Tua Tagovailoa — BENCHED


Bengals

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Dolphins

  • RB De'von Achane — Elite RB1


Bengals

  • QB Joe Burrow — Elite QB1 THIS WEEK

  • WR Ja'Marr Chase — Elite WR1

  • RB Chase Brown — Low-end RB1



Fantasy Starts:


Dolphins

  • TE Darren Waller — ELITE Streaming TE


Bengals

  • WR Tee Higgins — Mid-end WR2



Fantasy Flex / Risky Starts / Flex Appeal:


Dolphins

  • RB Jaylen Wright — Deep-league RB3/Low-End TD-Based Flex

  • K Riley Patterson — Strong Kicker streamer


Bengals

  • Bengals Defense — Deep-league Decent-Matchup Streaming Defense



Fantasy Sits / Fades:


Dolphins

  • Dolphins Defense — 21% Started

  • WR Jaylen Waddle — 76% Started


Bengals

  • None



Sneaky / Streamer Plays:


Dolphins

  • RB Jaylen Wright — 1% rostered

  • TE Darren Waller — 8% rostered

  • K Riley Patterson — 3% rostered


Bengals

  • Bengals Defense — 2% Started



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Bengals 27 - Dolphins 17


Dolphins

  • QB Quinn Ewers - 157 pass yards, 1 pass TD, 2 INTs

  • RB De'Von Achane - 20 carries, 144 rush yards, 1 rush TD, 4 catches, 48 rec yards

  • RB Jaylen Wright - 8 carries, 29 rush yards, 2 catches, 8 rec yards

  • WR Jaylen Waddle - 3/36

  • WR Malik Washington - 2/16

  • TE Darren Waller - 4/49/1

  • K Riley Patterson - 1/1 FG, 2/2 PAT


Bengals

  • QB Joe Burrow - 291 pass yards, 3 pass TDs

  • RB Chase Brown - 13 carries, 43 rush yards, 6 catches, 38 rec yards

  • RB Samaje Perine - 11 carries, 40 rush yards, 1 catch, 6 rec yards

  • WR Ja'Marr Chase - 8/109/1

  • WR Tee Higgins - 6/85/1

  • WR Andre Iosivas - 2/24

  • TE Mike Gesicki - 4/32/1

  • K Evan McPherson - 2/2 FG, 3/3 PAT


Betting Plays:

  • Greg Dulcich longest recception OVER 12.5 yards

  • De'Von Achane longest rush OVER 18.5 yards

  • De'Von Achane anytime TD

  • Greg Dulcich OVER 19.5 yards

  • Darren Waller OVER 22.5 yards

  • Jaylen Waddle UNDER 51.5 yards

  • Malik Washington UNDER 18.5 yards

  • De'Von Achane OVER 81.5 rush yards

  • Longshot TD: Darren Waller


Atlanta Falcons @ Arizona Cardinals — Sunday, Week 16, 4:05 PM ET


Quick Take:


This NFC matchup is expected to be close, with Atlanta slightly favored due to a more stable passing game and fewer injuries at skill positions. Arizona leans on Jacoby Brissett and Michael Wilson to generate offense, while Atlanta spreads the ball to multiple receivers. Fantasy production will likely hinge on passing volume and red-zone opportunities, making it a game with moderate upside for top receivers.


Pick: Falcons win — likely cover (ATL +1).



Injury Report:


Falcons

  • WR Drake London — QUESTIONABLE


Cardinals

  • RB Bam Knight — OUT REST OF SEASON / IR

  • WR Marvin Harrison — QUESTIONABLE



Fantasy Start & Forget It:


Falcons

  • RB Bijan Robinson — Top 5 RB start


Cardinals

  • TE Trey McBride — Top TE start



Fantasy Starts:


Falcons

  • TE Kyle Pitts — Top TE start


Cardinals

  • QB Jacoby Brissett — High-End Streaming QB

  • WR Michael Wilson — WR2/Flex (START & FORGET IT IF NO MARV)



Fantasy Flex / Risky Starts / Flex Appeal:


Falcons

  • Falcons Defense— Mid-End Streaming Defense


Cardinals

  • RB Michael Carter — Volume-based flex



Fantasy Sits / Fades:


Falcons

  • K Zane Gonzalez — 1% started


Cardinals

  • K Chad Ryland — 1% started



Sneaky / Streamer Plays:


Falcons

  • Falcons Defense — 14% rostered


Cardinals

  • RB Michael Carter — 3% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Falcons 24 - Cardinals 17


Falcons

  • QB Kirk Cousins - 288 pass yards, 2 pass TDs, 1 INT

  • RB Bijan Robinson - 14 carries, 84 rush yards, 1 rush TD, 3 catches, 34 rec yards

  • RB Tyler Allgeier - 9 carries, 38 rush yards, 1 catch, 5 rec yards

  • WR Drake London (IF ACTIVE) - 7/89/1

  • WR Darnell Mooney - 2/29

  • WR David Sills - 3/23

  • TE Kyle Pitts - 6/54/1

  • K Zane Gonzalez - 1/2 FG, 3/3 PAT


Cardinals

  • QB Jacoby Brissett - 304 pass yards, 2 pass TDs, 1 INT, 4 carries, 26 rush yards

  • RB Michael Carter - 14 carries, 51 rush yards, 4 catches, 37 rec yards

  • WR Michael Wilson - 9/96/1

  • TE Trey McBride - 9/87/1

  • K Chad Ryland - 1/2 FG, 2/2 PAT


Betting Plays:

  • Michael Carter longest reception OVER 10.5 yards

  • Kyle Pitts longest reception OVER 18.5 yards

  • Bijan anytime TD

  • Trey McBride OVER 6.5 receptions

  • Michael Carter OVER 19.5 rec yards

  • Bijan OVER 34.5 rec yards

  • Jacoby Brissett OVER 15.5 rush yards

  • Jacoby Brissett OVER 245.5 pass yards

  • Jacoby Brissett OVER 1.5 pass TDs

  • Longshot TD: Tyler Allgeier

  • Longshot TD: Michael Carter

  • Longshot TD: Bijan 2+


Jacksonville Jaguars @ Denver Broncos — Sunday, Week 16, 4:05 PM ET


Quick Take:


Denver hosts Jacksonville in a matchup where the Broncos’ defense and home-field advantage give them a slight edge. Jacksonville’s fantasy value is concentrated in Travis Etienne Jr. and Jakobi Meyers, while Denver leans on Courtland Sutton and a steady defensive scheme. Expect a methodical game where big plays are scarce, and fantasy scoring comes primarily through volume touches and targets.


Pick: Broncos win — DEN cover (DEN -3).



Injury Report:


Jaguars

  • No listed injuries impacting fantasy this week


Broncos

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Jaguars

  • None


Broncos

  • None



Fantasy Starts:


Jaguars

  • RB Travis Etienne Jr — Low-End RB2 (BAD MATCHUP)

  • WR Jakobi Meyers — Solid WR2

  • K Cam Little — Top streaming Kicker


Broncos

  • Broncos Defense — Top streaming D/ST

  • K Will Lutz — Top streaming Kicker



Fantasy Flex / Risky Starts / Flex Appeal:


Jaguars

  • Jaguars Defense — Solid D/ST

  • TE Brenton Strange — High-End TE2


Broncos

  • QB Bo Nix — 55% started

  • WR Courtland Sutton — TD upside



Fantasy Sits / Fades:


Jaguars

  • QB Trevor Lawrence — 66% started

  • WR Brian Thomas Jr — 75% rostered

  • Jaguars Defense — 44% rostered


Broncos

  • RB RJ Harvey — 60% started

  • WR Troy Franklin — 34% started



Sneaky / Streamer Plays:


Jaguars

  • None


Broncos

  • Broncos Defense — 77% rostered

  • K Will Lutz — 71% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Broncos 20 - Jaguars 17


Jaguars

  • QB Trevor Lawrence - 168 pass yards, 1 pass TD, 1 INT, 5 carries, 35 rush yards

  • RB Travis Etienne Jr - 17 carries, 64 rush yards, 1 rush TD, 2 catches, 23 rec yards

  • RB LeQuint Allen Jr - 4 carries, 18 rush yards, 3 catches, 13 rec yards, 1 rec TD

  • WR Jakobi Meyers - 5/66

  • WR Brian Thomas Jr - 3/37

  • WR Parker Washington - 2/24

  • TE Brenton Strange - 3/28

  • K Cam Little - 1/1 FG, 2/2 PAT


Broncos

  • QB Bo Nix - 177 pass yards, 2 pass TDs, 1 INT, 3 carries, 32 rush yards

  • RB RJ Harvey - 14 carries, 44 rush yards, 4 catches, 27 rec yards, 1 rec TD

  • WR Courtland Sutton - 2/38/1

  • WR Troy Franklin - 4/29

  • WR Pat Bryant - 2/24

  • TE Evan Engram - 3/24

  • K Will Lutz - 2/2 FG, 2/2 PAT



Betting Plays:

  • Parker Washington longest reception OVER 14.5 yards

  • Brenton Strange longest reception 16.5 yards

  • BTJ longest reception OVER 21.5 yards

  • Travis Etienne Jr anytime TD

  • Trevor Lawrence OVER 0.5 INTs

  • Bo Nix OVER 0.5 INTs

  • Brenton Strange UNDER 39.5 yards

  • Bo Nix UNDER 239.5 pass yards

  • Longshot TD: Jags OR Broncos Defense


Detroit Lions @ Pittsburgh Steelers — Sunday, Week 16, 4:25 PM ET


Quick Take:


Detroit travels to Pittsburgh in a game that favors the Lions due to a more efficient offense and fewer major injuries. The Steelers’ fantasy value is concentrated in DK Metcalf and sometimes the Jaylen Warren/Kenneth Gainwell tandem, but the Lions’ balanced attack and Jared Goff’s volume should allow them to control the tempo. Expect a high-scoring contest that could come down to late drives or special teams plays.


Pick: Lions win — DET cover (DET -6.5).



Injury Report:


Lions

  • TE Sam LaPorta — OUT


Steelers

  • EDGE TJ Watt — DOUBTFUL



Fantasy Start & Forget It:


Lions

  • RB Jahmyr Gibbs — Solid QB1

  • WR Amon-Ra St. Brown — Elite WR1


Steelers

  • None



Fantasy Starts:


Lions

  • QB Jared Goff — Solid QB1 (GOOD MATCHUP)

  • WR Jameson Williams — WR1/2

  • RB David Montgomery — TD-Dependent RB2 (GREAT MATCHUP)


Steelers

  • WR DK Metcalf — WR1/2

  • K Chris Boswell — Reliable Kicker



Fantasy Flex / Risky Starts / Flex Appeal:


Lions

  • K Jake Bates — Decent Kicker

  • Lions Defense — Decent D/ST


Steelers

  • RB Kenneth Gainwell — Low-End RB2 PPR

  • TE Pat Freiermuth — Boom/bust TE



Fantasy Sits / Fades:


Lions

  • None


Steelers

  • QB Aaron Rodgers — 3% Started

  • RB Jaylen Warren — 63% Started



Sneaky / Streamer Plays:


Lions

  • Lions Defense — 39% Rostered


Steelers

  • K Chris Boswell — 66% rostered



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Lions 34 - Steelers 24


Lions

  • QB Jared Goff - 319 pass yards, 2 pass TDs

  • RB David Montgomery - 7 carries, 41 rush yards, 1 rush TD, 2 catches, 12 rec yards

  • RB Jahmyr Gibbs - 15 carries, 121 rush yards, 1 rush TD, 5 catches, 44 rec yards

  • WR Jameson Williams - 6/105/1

  • WR Amon-Ra St. Brown - 9/118/1

  • WR Isaac TeSlaa - 2/26

  • K Jake Bates - 2/2 FG, 4/4 PAT


Steelers

  • QB Aaron Rodgers - 277 pass yards, 2 pass TDs

  • RB Kenneth Gainwell - 11 carries, 41 rush yards, 5 catches, 36 rec yards

  • RB Jaylen Warren - 11 carries, 37 rush yards, 1 rush TD, 2 catches, 14 rec yards

  • WR DK Metcalf - 5/63/1

  • TE Pat Freiermuth - 3/38/1

  • K Chris Boswell - 1/1 FG, 3/3 PAT



Betting Plays:

  • David Montgomery longest reception OVER 8.5 yards

  • Amon-Ra St. Brown longest reception OVER 23.5 yards

  • Jahmyr Gibbs longest rush OVER 16.5 yards

  • Jahmyr Gibbs anytime TD

  • Amon-Ra St. Brown anytime TD

  • DK Metcalf anytime TD

  • DK Metcalf OVER 55.5 yards

  • Jared Goff OVER 1.5 pass TDs

  • Longshot TD: Pat Freiermuth

  • Longshot TD: David Montgomery


Houston Texans @ Las Vegas Raiders — Sunday, Week 16, 4:25 PM ET


Quick Take:


Houston travels to Las Vegas in a matchup that favors the Texans due to Raiders’ inconsistency EVERYWHERE. The Texans’ fantasy production centers on Nico Collins, Woody Marks and Dalton Schultz, their defense, and their kicker Ka'imi Fairbairn, while the Raiders rely heavily on volume-based RB Ashton Jeanty and TE scoring from top-5 TE Brock Bowers. Houston should control tempo early, and this game should result in a blowout in favor of the Texans, with a negative game script likely for the Raiders.


Pick: Texans win — likely cover (HOU -11.5).



Injury Report:


Texans

  • RB Woody Marks — QUESTIONABLE

  • RB Nick Chubb — QUESTIONABLE


Raiders

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Texans

  • WR Nico Collins — Elite WR1

  • K Ka’imi Fairbairn — Top 5 kicker

  • Texans Defense — Top 5 Defense


Raiders

  • None



Fantasy Starts:


Texans

  • QB CJ Stroud — QB2/Flex upside

  • RB Woody Marks — RB2/Flex

  • TE Dalton Schultz — Streaming TE


Raiders

  • None



Fantasy Flex / Risky Starts / Flex Appeal:


Texans

  • WR Jayden Higgins — Matchup-dependent flex


Raiders

  • None



Fantasy Sits / Fades:


Texans

  • None


Raiders

  • RB Ashton Jeanty — 90% started

  • TE Brock Bowers — 99% started

  • EVERYONE ELSE



Sneaky / Streamer Plays:


Texans

  • QB CJ Stroud — 29% rostered

  • RB Woody Marks — 48% rostered

  • TE Dalton Schultz — 25% rostered


Raiders

  • None



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Texans 34 - Raiders 7


Texans

  • QB CJ Stroud - 248 pass yards, 3 pass TDs, 2 carries, 14 rush yards

  • RB Woody Marks - 16 carries, 73 rush yards, 1 rush TD, 1 catch, 6 rec yards

  • WR Nico Collins - 5/107/1

  • WR Jayden Higgins - 4/31/1

  • TE Dalton Schultz - 5/51/1

  • K Ka’imi Fairbairn - 2/2 FG, 4/4 PAT



Raiders

  • QB Geno Smith - 136 pass yards, 1 pass TD, 2 INTs, 4 carries, 6 rush yards

  • RB Ashton Jeanty - 14 carries, 42 rush yards, 4 catches, 31 rec yards

  • WR Tre Tucker - 2/20

  • WR Jack Bech - 3/27

  • TE Brock Bowers - 4/54/1

  • K Daniel Carlson - 0/1 FG, 1/1 PAT



Betting Plays:

  • Texans -11.5

  • Nico Collins OVER 60.5 yards

  • CJ Stroud OVER 1.5 pass TDs

  • Geno Smith OVER 0.5 IINTs

  • Ashton Jeanty UNDER 51.5 rush yards

  • Dalton Schultz OVER 3.5 receptions

  • Longshot TD: Dalton Schultz


New England Patriots @ Baltimore Ravens — Sunday, Week 16, 8:20 PM ET


Quick Take:


This late-night matchup features two AFC teams with complementary strengths. The Ravens lean on their rushing attack and efficient QB play by Lamar as of late, while New England relies on Drake Maye, Treveyon Henderson, and Stefon Diggs to generate consistent fantasy production. Expect a close, methodical game where touchdowns and red-zone opportunities will be key to fantasy outcomes.


Pick: Patriots win — likely cover (NE -2).



Injury Report:


Patriots

  • No listed injuries impacting fantasy this week


Ravens

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


Patriots

  • None


Ravens

  • QB Lamar Jackson — Solid QB1

  • RB Derrick Henry — Solid RB1



Fantasy Starts:


Patriots

  • QB Drake Maye — Solid QB1

  • RB Treveyon Henderson — Risky High-End RB2 WITH MAJOR UPSIDE

  • WR Stefon Diggs — Low-End WR2


Ravens

  • WR Zay Flowers — Solid WR2



Fantasy Flex / Risky Starts / Flex Appeal:


Patriots

  • TE Hunter Henry — Red-zone dependent


Ravens

  • TE Mark Andrews — TE2/Flex

  • TE Isaiah Likely — TE2/Flex



Fantasy Sits / Fades:


Patriots

  • None


Ravens

  • K Tyler Loop — 55% started



Sneaky / Streamer Plays:


Patriots

  • WR Kayshon Boutte — 2% rostered

  • TE Hunter Henry — 56% rostered


Ravens

  • None



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: Patriots 27 - Ravens 23


Patriots

  • QB Drake Maye - 277 pass yards, 3 pass TDS, 1 INT, 6 carries, 13 rush yards

  • RB Treveyon Henderson - 14 carries, 68 rush yards, 3 catches, 31 rec yards, 1 rec TD

  • RB Rhamondre Stevenson - 11 carries, 34 rush yards, 2 catches, 26 rec yards

  • WR Stefon Diggs - 7/76/1

  • WR Kayshon Boutte - 3/68/1

  • WR Pop Douglas - 3/32

  • WR Mack Hollins- 4/36

  • TE Hunter Henry - 4/49

  • K Andy Borregales - 2/2 FG, 3/3 PAT


Ravens

  • QB Lamar Jackson - 217 pass yards, 1 pass TD, 1 INT, 6 carries, 39 rush yards

  • RB Derrick Henry - 17 carries, 104 rush yards, 1 rush TD, 2 catches, 13 rec yards

  • WR Zay Flowers - 4/70

  • TE Isaiah Likely - 4/23

  • TE Mark Andrews - 3/43

  • K Tyler Loop - 3/3 FG, 2/2 PAT



Betting Plays:

  • D-Hop longest reception OVER 8.5 yards

  • Pop Douglas longest reception OVER 12.5 yards

  • Hunter Henry longest reception OVER 17.5 yards

  • Derrick Henry longest rush OVER 18.5 yards

  • Keaton Mitchell longest rush OVER 10.5 yards

  • Treveyon Henderson longest rush OVER 13.5 yards

  • Derrick Henry anytime TD

  • Derrick Henry 80+ rush yards

  • Lamar 20+ rush yards

  • Lamar Jackson OVER 4.5 carries

  • Drake Maye 1+ INT

  • Longshot TD: Kayshon Boutte


San Francisco 49ers @ Indianapolis Colts — Monday, Week 16, 8:15 PM ET


Quick Take:


San Francisco enters this matchup as the clear favorite, with a strong running game and efficient QB play. The Colts will rely on Alec Pierce and Tyler Warren for fantasy production, but the 49ers’ defense and balanced offensive attack make them tough to beat at home. Expect a controlled game where touchdowns come primarily through high-efficiency drives and volume plays.


Pick: 49ers win — likely cover (SF -6.5).



Injury Report:


49ers

  • No listed injuries impacting fantasy this week


Colts

  • No listed injuries impacting fantasy this week



Fantasy Start & Forget It:


49ers

  • RB Christian McCaffrey — Elite RB1

  • TE George Kittle — Elite TE1


Colts

  • None



Fantasy Starts:


49ers

  • WR Jauan Jennings — Solid WR2

  • K Eddy Pineiro — Solid Kicker

  • 49ers Defense — Streaming D/ST


Colts

  • RB Jonathan Taylor — Solid RB1



Fantasy Flex / Risky Starts / Flex Appeal:


49ers

  • QB Brock Purdy — Solid QB1

  • WR Ricky Pearsall (IF ACTIVE) — High-End WR3

  • WR Kendrick Bourne (IF NO PEARSALL)— High-End WR3


Colts

  • WR Josh Downs — TD Upside



Fantasy Sits / Fades:


49ers

  • None


Colts

  • WR Alec Pierce — 56% Started

  • WR Michael Pittman Jr — 71% Started

  • TE Tyler Warren — 77% Started

  • Colts Defense — 47% Started



Sneaky / Streamer Plays:


49ers

  • 49ers Defense — 13% rostered


Colts

  • None



BOX SCORE PREDICTIONS (FANTASY RELEVANT ONLY):


SCORE: 49ers 27 - Colts 16


49ers

  • QB Brock Purdy - 276 pass yards, 2 pass TDs, 1 INT, 4 carries, 29 rush yards

  • RB Christian McCaffrey - 19 carries, 62 rush yards, 1 rush TD, 4 catches, 42 rec yards

  • RB Brian Robinson Jr - 7 carries, 28 rush yards

  • WR Jauan Jennings - 5/52/1

  • WR Ricky Pearsall (IF ACTIVE) - 3/37

  • WR Kendrick Bourne - 2/19

  • TE George Kittle - 7/74/1

  • K Eddy Pineiro - 2/2 FG, 3/3 PAT


Colts

  • QB Philip Rivers - 166 pass yards, 1 INT

  • RB Jonathan Taylor - 24 carries, 109 rush yards, 1 rush TD, 3 catches, 13 rec yards

  • WR Alec Pierce - 2/23

  • WR Michael Pittman Jr - 3/31

  • WR Josh Downs - 3/19

  • TE Tyler Warren - 4/28

  • K Blake Grupe - 3/3 FG , 1/1 PAT



Betting Plays:

  • George Kittle longest reception OVER 20.5 yards

  • Brock Purdy longest rush OVER 7.5 yards

  • CMC anytime TD

  • Jauan Jennings anytime TD

  • George Kittle anytime TD

  • George Kittle50+ yards

  • George Kittle 5+ catches

  • Jauan Jennings 4+ catches

  • Tyler Warren UNDER 4.5 catches

  • Jonathan Taylor OVER 19.5 carries

  • Jonathan Taylor OVER 2.5 receptions

  • Philip Rivers 1+ INT

  • Michael Pittman Jr UNDER 4.5 receptions

  • Longshot TD: CMC 2+


TOP 10 STARTS

  1. Lions WR Jameson Williams 51% Started 

  2. Bears WR DJ Moore 42% Started 

  3. Steelers WR DK Metcalf 55% Started 

  4. Rams TE Colby Parkinson 13% Started 

  5. Packers QB Jordan Love 51% Started 

  6. Packers WR Jayden Reed 21% Started 

  7. Bears RB D’Andre Swift 71% Started 

  8. Packers RB Emmanuel Wilson 22% Started 

  9. Cardinals QB Jacoby Brissett 41% Started 

  10. 49ers QB Jauan Jennings 44% Started 


TOP 10 SITS

  1. Jets RB Breece Hall 64% Started

  2. Raiders RB Ashton Jeanty 90% Started 

  3. Seahawks RB Kenneth Walker III 68% Started 

  4. Steelers RB Jaylen Warren 55% Started 

  5. Cowboys TE Jake Ferguson 58% Started 

  6. Colts WR Alec Pierce 56% Started

  7. Colts TE Tyler Warren 77% Started

  8. Raiders TE Brock Bowers 99% Started 

  9. Broncos QB Bo Nix 42% Started 

  10. Vikings WR Justin Jefferson 95% Started 


Jake's 5 LOCKS Parlay of the Week:

  1. Jacoby Brissett OVER 245.5 pass yards -112

  2. Jacoby Brissett OVER 1.5 pass TDs -121

  3. D'Andre Swift OVER 12.5 rush attempts -125

  4. De'Von Achane OVER 83.5 rush yards -110

  5. Michael Carter OVER 18.5 rec yards -118


VALUE: +2095 -- $10 --> $209.48

 
 
 

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